Organic Hemp CBD Oil

Organic Hemp CBD OIL

 

High Strength Herbal Hemp CBD as a Supplement for General Health Support

Here in the UK and in many other countries around the world Hemp CBD oil is classified as a dietary food supplement.

Our products originate from a licensed farm from organic European industrial hemp plants. Our hemp is extracted by a super critical CO2 process of the whole plant and is put through regular testing to achieve the highest potency and purity.
Because quality matters, Herbactive make plants work.

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Dear Alan,
Thank you so much for prompt dispatch of the products I ordered. I am very appreciative of your knowledge and professionalism.
Christopher.

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The tonics arrived yesterday - Black Salve and Personal Tonic -  and I started on the personal tonic immediately. I also started using the 20% oil and have found to my relief that it works - so many others haven’t.
Thanking you, MT

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Full-spectrum Cannabinoid Extract
The enterage effect: Apart from the full-spectrum cannabinoids found in Herbactive CBD Oil (see a complete list below) there are many other constituents in our organic hemp. These include: Vitamins, Glycosides, Flavanoids, Alkanes, Aldehydes, Nitrogenous compounds, Amino acids, Oils, Alcohols, Ketones, Sugars, Pigments, Water.

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Hi Alan, First week of taking your 5% CBD Oil is showing good signs. Hoping this is the missing link for me. Karen. London.

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What Is CBD? 
Our CBD is a whole oil extract from a whole herb plant and is part of the huge range of herbal medicines available at Herbactive Health Clinic. Cannabidiol (CBD) is a fatty acid that comes from the hemp plant. CBD oil is a mixture of various natural substances as they are derived from hemp. Hemp (also known as agricultural hemp, industrial hemp) is cultivated for use as rope, paper, textiles, clothing, biodegradable plastics, construction (e.g. Hempcrete and insulation), bio-fuel, cosmetics, oil, health food. This hybrid grows up to 15 feet (5m) high with a bamboo-like stem and looks completely different to the marijuana plant which is only 5 feet (1.7m) in height and bushy. They both come from the Cannabis sativa L. plant, but the hemp hybrid Herbactive uses has just a trace of the psychoactive constituent (THC) found in the marijuana plant. It is specifically cultivated for its very high CBD content.
The production of hemp oil involves extracting the fatty acids from the hemp plant. Cannabinoids are fat-soluble so they come out of the plant via oil extraction. As hemp is naturally high in CBD and contains only traces of THC (the chemical that give the high), the hemp oil produced from it is safe and non-psychotropic. Herbactive has sourced a high CBD hemp oil from a breed that has been developed over many years and is cultivated with licensed EU farmers. Our CBD oils and products do not have any psychoactive effects and are used entirely for general health purposes under UK law. Cannabidiol (CBD) is one of at least 112 active cannabinoids identified in cannabis. CBD is considered to have a wide scope of potential medical applications with no side effects.

It is also notable that humans make certain cannabinoids in our bodies which are activated to counteract pain and also to restore health during illness.

Constituents in Hemp Oil 
Hemp contains well over a hundred different phytocannabinoids, most notably cannabidiol (CBD), CBC, CBG, CBN, trace (legal) amounts of THC (tetrahydrocannabinol) and probably others yet to be identified. In addition to the phytocannabinoids present in our whole hemp plant extracts, there are also many other types of natural molecules and phytochemical compounds such as amino acids, carbohydrates, vitamins (including B1, B2, B6, D, & E), fatty acids (including omega 3 & 6), trace minerals (including iron, zinc, calcium, magnesium, & potassium), carotene, chlorophyll, flavonoids, ketones, nitrogenous compounds, alkanes, alcohols, glycosides, pigments, hemp seed oil, water, and terpenes. The most common terpenes in our CBD oils are myrcene, beta-caryophyllene, terpinolene, linalool, alpha-Pinene, beta-pinene, nerolidol or phytol, trans-alpha-bergamotene, limonene/beta-phellandrene (co-elution), alpha-humulene, (E)-beta-farnesene, and delta-3-Carene.

Oxford University Research Programme
Oxford University has announced a new £10m research programme into the medical uses of the cannabinoids in cannabis. Scientists will explore the potential benefits of the compounds in cannabis in an attempt to create new treatments for conditions including pain, cancer and inflammatory diseases. Zameel Cader, associate professor in clinical neurosciences, said the use of cannabis compounds was an "area of huge untapped potential". Dr Cader said the research would focus on an area of the brain known as the endocannabinoid system which plays a role in mood, memory and the sensation of pain. The endocannabinoid system is complex and "impacts on many aspects of brain function and the way that synapses operate", said Dr Cader. "It's also really important in the way the immune response is governed. We know that it's particularly important for many neurological disorders."
"The research programme will develop results into innovative therapies designed to help improve the quality of life of millions of patients," said the University spokesman. Researchers "will seek to identify cutting edge medical therapies through research into the molecular, cellular and systems mechanisms of cannabinoids," it said. It will include study of Alzheimer's, Parkinson's, migraine, auism and epilepsy.
"There are [approaching 120] different cannabinoids, most of which we don't know what their actions are," Dr Cader said.
With thanks to The Independant, UK national newspaper, online; edited. June 2017.

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Hi Alan, I'm in my late 40s and I have always jogged almost every day. I can jog for long distances. But recently my recovery time has been slower; my joints and muscles ache as I've never known. And for some reason my sleep has been affected. I read about your CBD Oil on your website. So I decided to try your 3% CBD oil. I took just 3-5 drops a day. Within a week I was feeling better and sleeping better. My recovery is much quicker and I don't get joint and muscle ache like I used to. Thanks for that and I will continue on this low dose because it seems to do me a lot of good! Jim. Christchurch, Dorset.

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What is CBD used for? 
The National Cancer Institute (USA) website states: The potential benefits of medicinal Cannabis for people living with cancer include antiemetic effects, appetite stimulation, pain relief, and improved sleep…for symptom management.

It is said to be neuroprotectant, an antioxidant, an analgesic (pain relief), an anxiolytic (anxiety, stress, panic), and early research suggests it may stop tumours from spreading.

One science paper (Journal of Cancer Research 2004:08:15) says that cannabinoids could stop the action of VEGF (Vascular Endothelial Growth Factor) which is used by cancer tumours to stimulate blood vessel growth to spread. There is a huge body of research that claims that cannabinoids may cause antitumour effects by induction of cell death, inhibition of cancer cell growth, and inhibition of tumour angiogenesis and metastasis, and that they appear to kill tumour cells but do not affect surrounding healthy cells.
NB Herbactive does not prescribe CBD Oil to treat any cancer. CBD Oil may only be used as a health supplement as a preventative against the development of cancers. Alan Hopking, herbal practitioner, cannot advise anyone about the treatment of cancer. His advice is for maintenance of health to avoid illnesses and serious disease. We prescribe this herbal medicine as a preventative only.

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For the last 6 weeks I've been giving 5 drops of your CBD Oil to my husband who suffered a stroke which affected his speech. I'm really amazed that he is speaking better, more clearly and using longer sentences recently. This change is very noticeable to me. I'm really pleased of course and thank you for all your advice and directions of the use of this remarkable oil about which we have all heard so much over the years. M.J. Dorset.

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Research also showed that CBD acted by blocking a gene responsible for metastases (the Id-1 gene) which causes aggressive movement of abnormal cells away from a tumour site. This was shown in trials with both brain tumours and breast tumours.

In summary, research shows that CBD is indicated for: Pain relief. Nausea. Seizures. Anxiety, stress, worry. Depression. Muscle relaxant. Antimicrobial. Antibacterial. Protects the nervous system. Anti-diabetic (improves the action of the pancreas on insulin). Improves blood circulation (enhances wound healing; reduces cold hands & feet). Improves psoriasis and other skin diseases. Relieves Crohn’s disease, diverticulitis, and IBS. Anti-inflammatory. Bone stimulant (helps osteoporosis and painful bones). Arthritis. Antioxidant.

The cannabinoids are also known as neuroprotectants, for example in limiting neurological damage following ischemic events, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as MS, Alzheimer’s, Parkinson’s disease and HIV dementia.

In a study published in the journal Nature Medicine investigating the brain systems involved in the ageing process led by Andras Bilkei-Gorzo from the University of Bonn, Germany, to show that the brain's endocannabinoid system, which affects mood memory and sensations such as pain, and which actively declines with age, "can restore signalling to a normal level" and "restore the cognitive ability of the old" when given a low dose of a compound of CBD/THC oil, and improves learning and memory. This system did not respond as well when not give the compound. Michael Bloomfield from University College London, said the "well conducted" study was "exciting" as it "opens up a whole new chemical system called the endocannabinoid system, as a potential target for new avenues of research which could include illnesses like dementia."

CBD reduces high blood pressure

Oral CBD administration is associated with reduced blood pressure in healthy volunteers, according to clinical trial data published online in the Journal of Clinical Investigation. Investigators from the University of Nottingham in the United Kingdom assessed the effects of a single oral dose of 600 mg of CBD extract versus placebo in nine male subjects. Cannabidiol administration reduced resting systolic blood pressure and stroke volume (the amount of blood pumped by the left ventricle of the heart in one contraction). Compared to placebo, CBD intake was associated with reduced BP levels following exercise and in response to stress. Increased heart rate was observed following CBD administration, but no “adverse events” were reported by participants either during or following the study sessions.

Authors concluded:

“Our data show that a single dose of CBD reduces resting blood pressure and the blood pressure response to stress, particularly cold stress, and especially in the post-test periods. This may reflect the anxiolytic and analgesic effects of CBD, as well as any potential direct cardiovascular effects. … Further research is also required to establish whether CBD has any role in the treatment of cardiovascular disorders such as a hypertension.”

Report edited from article in the online Daily Chronical, June 2017.

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Hello Alan. I started using your 20% CBD oil just over 6 months ago for a brain tumour. I also used your Skullcap tincture to help the pain. I refused surgery and chemo - I am too old for that and it went against my instincts. I have just had extensive brain scans from different angles to assess the progress of the tumour. They couldn't find it!! The consultant had to admit that it had disappeared and that he couldn't understand it. Obviously I was astounded and overjoyed. I will continue with your treatment of course. Thank you for all your help. Name withheld. UK

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How is CBD Hemp Oil made? 
A lot of plant material and many steps are required to produce a comparatively very small amount of CBD oil. Herbactive uses a specifically developed organic hemp hybrid that has taken many years of dedicated cultivation to get it to this point where it has been licensed for agricultural cultivation and harvest for medicinal application. The extraction process is done with purity in mind and for the maximising of the CBDs in the oil, which is then extensively tested to ensure its quality.

How is CBD oil used?
Internal: The dose is usually 2-10 drops under the tongue 1-2 times daily (max daily dose 20 drops).
External: CBD oil as a cream or lotion can be applied to the area of the pain e.g. joints, spine, muscles, tendons, etc. or applied to skin complaints e.g. psoriasis, dermatitis, wounds, acne, allergy rash, bites.

Strength of Herbactive Organic Hemp CBD Oil
​3% with an entourage effect of 30mg CBD per ml. Sizes available 10ml (total CBD value 300mg) 30ml (total CBD value 900mg) 50ml (total CBD value 1500mg)
5% with an entourage effect of 50mg CBD per ml. Sizes available 10ml (total CBD value 500mg) 30ml (total CBD value 1500mg) 50ml (total CBD value 2500mg)
20% with an entourage effect of 200mg CBD per ml. Sizes available 10ml (total CBD value 2000mg) 30ml (total CBD value 6000mg) 50ml (total CBD value 10000mg)

See our webstore for prices.

The Medicines and Healthcare Products Regulatory Agency (MHRA) has recently acknowledged that there are significant health benefits associated with CBD. However, as a result they have come to the opinion that products containing Cannabidiol (CBD) may require a product license to sell in the UK, if recommended for medical purposes. Herbactive, however, makes no such medical claims. Our CBD Oil is not sold as a medicine. Herbactive Organic CBD Hemp Oil product is a food supplement with the oil containing the whole range of naturally occurring cannabinoids and many other naturally occuring constituents found in the fresh plant (i.e. our CBD Oil is not an isolated or standardised extract of cannabinoids alone, created by hi-tech chemical extraction,synthesis or manufacture). Herbactive Hemp CBD Oil is extracted from the whole hemp plant and our products help maintain a person’s wellbeing by supporting the body’s natural endocannabinoid system.
We are committed to providing quality products to support people leading healthy lives. Herbactive was founded by Alan Hopking who is a passionate believer in natural health from herbs and organic foods and supplements. He is committed to publishing educational information about health and healthy lifestyle (with a bias towards herbs and herbalism!).

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More information

Chemistry and Diversity of the Hemp Cannabinoids

A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells that alter neurotransmitter release in the brain. Ligands for these receptor proteins include the endocannabinoids (produced naturally in the body by animals),[1] the phytocannabinoids (found in cannabis and some other plants), and synthetic cannabinoids (manufactured artificially). The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis.[2][3] Cannabidiol (CBD) is another major constituent of the plant.[4] There are at least 113 different cannabinoids isolated from cannabis, exhibiting varied effects.[5]

Synthetic cannabinoids encompass a variety of distinct chemical classes: the classical cannabinoids structurally related to THC, the nonclassical cannabinoids (cannabimimetics) including the aminoalkylindoles, 1,5-diarylpyrazoles, quinolines, and arylsulfonamides, as well as eicosanoids related to endocannabinoids.[2]

Cannabinoid receptors

Phytocannabinoids

Cannabigerol-type CBG

Cannabichromene-type CBC

Cannabidiol-type CBD

Tetrahydrocannabinol- and Cannabinol-type THC, CBN

Cannabielsoin-type CBE

iso-Tetrahydrocannabinol-typeiso-THC

Cannabicyclol-type CBL

Cannabicitran-type CBT

Main classes of natural cannabinoids

The bracts surrounding a cluster of Cannabis sativa flowers are coated with cannabinoid-laden trichomes

Cannabis-derived cannabinoids

The classical cannabinoids are concentrated in a viscous resin produced in structures known as glandular trichomes. At least 113 different cannabinoids have been isolated from the Cannabis plant[5] To the right, the main classes of cannabinoids from Cannabis are shown. The best studied cannabinoids include tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN).

Types

All classes derive from cannabigerol-type (CBG) compounds and differ mainly in the way this precursor is cyclized.[12] The classical cannabinoids are derived from their respective 2-carboxylic acids (2-COOH) by decarboxylation (catalyzed by heat, light, or alkaline conditions).[13]

THC (Tetrahydrocannabinol)

THCA (Tetrahydrocannbinolic acid)

CBD (Cannabidiol)

CBDA (Cannabidiolic Acid)

CBN ((Cannabinol)

CBG (Cannabigerol)

CBC (Cannabichromene)

CBL (Cannabicyclol)

CBV (Cannabivarin)

THCV (Tetrahydrocannabivarin)

CBDV (Cannabidivarin)

CBCV (Cannabichromevarin)

CBGV (Cannabigerovarin)

CBGM (Cannabigerol Monomethyl Ether)

CBE (Cannabielsoin)

CBT (Cannabicitran)

Tetrahydrocannabinol

Tetrahydrocannabinol (THC) is the primary psychoactive component of the Cannabis plant. Delta-9-tetrahydrocannabinol (Δ9-THC, THC) and delta-8-tetrahydrocannabinol (Δ8-THC), through intracellular CB1 activation, induce anandamide and 2-arachidonoylglycerol synthesis produced naturally in the body and brain. These cannabinoids produce the effects associated with cannabis by binding to the CB1cannabinoid receptors in the brain.

Cannabidiol

Cannabidiol (CBD) is non-psychotropic. Recent evidence shows that the compound counteracts cognitive impairment associated with the use of cannabis.[14] Cannabidiol has little affinity for CB1 and CB2 receptors but acts as an indirect antagonist of cannabinoid agonists.[15] It was found to be an antagonist at the putative new cannabinoid receptor, GPR55, a GPCR expressed in the caudate nucleus and putamen.[16] Cannabidiol has also been shown to act as a 5-HT1A receptor agonist.[17] CBD can interfere with the uptake of adenosine, which plays an important role in biochemical processes, such as energy transfer.[citation needed] It may play a role in promoting sleep and suppressing arousal.[18]

CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC.[19]

There is tentative evidence that CBD had an anti-psychotic effect, but research in this area is limited.[20][14]

Cannabinol

Cannabinol (CBN) is the primary product of THC degradation, and there is usually little of it in a fresh plant.[citation needed] CBN content increases as THC degrades in storage, and with exposure to light and air.[citation needed] It is only mildly psychoactive. Its affinity to the CB2receptor is higher than for the CB1 receptor.[21]

Cannabigerol

Cannabigerol (CBG) is non-psychoactive but still contributes to the overall effects of Cannabis. CBG has been shown to promote apoptosis in cancer cells and inhibit tumor growth in mice.[22] It acts as an α2-adrenergic receptor agonist, 5-HT1A receptor antagonist, and CB1 receptor antagonist.[23] It also binds to the CB2 receptor.[23]

Tetrahydrocannabivarin

Tetrahydrocannabivarin (THCV) is prevalent in certain central Asian and southern African strains of Cannabis.[24][25] It is an antagonist of THC at CB1 receptors and attenuates the psychoactive effects of THC.[26]

Cannabidivarin

Although cannabidivarin (CBDV) is usually a minor constituent of the cannabinoid profile, enhanced levels of CBDV have been reported in feral cannabis plants from the northwest Himalayas, and in hashish from Nepal.[25][27]

Cannabichromene

Cannabichromene (CBC) is non-psychoactive and does not affect the psychoactivity of THC.[28] CBC has shown antitumor effects in breast cancer xenoplants in mice.[29] More common in tropical cannabis varieties.

Biosynthesis

Cannabinoid production starts when an enzyme causes geranyl pyrophosphate and olivetolic acid to combine and form CBGA. Next, CBGA is independently converted to either CBG, THCA, CBDA or CBCA by four separate synthase, FAD-dependent dehydrogenase enzymes. There is no evidence for enzymatic conversion of CBDA or CBD to THCA or THC. For the propyl homologues (THCVA, CBDVA and CBCVA), there is an analogous pathway that is based on CBGVA from divarinolic acid instead of olivetolic acid.

Double bond position

In addition, each of the compounds above may be in different forms depending on the position of the double bond in the alicyclic carbon ring. There is potential for confusion because there are different numbering systems used to describe the position of this double bond. Under the dibenzopyran numbering system widely used today, the major form of THC is called Δ9-THC, while the minor form is called Δ8-THC. Under the alternate terpene numbering system, these same compounds are called Δ1-THC and Δ6-THC, respectively.

Adapted and Edited from Wikipedia – acknowledgements and thanks

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OTHER PLANTS AND CANNABINOIDS

For years, it was thought that cannabis was the only plant capable of producing cannabinoids. However, in the last few years research has been published that shows that cannabis is not the only plant that produces these compounds, and that they are actually quite common!

What exactly is a cannabinoid?

Cannabinoids are lipid-based molecules that all act to some degree on the cannabinoid receptors, which are a primary component of the endocannabinoid system. Cannabinoids are produced by plants (most famously, the cannabis plant), but are also produced by the bodies of humans and most other animal species, and can also be synthesized in laboratories.

Cannabinoids produced by plants are known as phytocannabinoids, those produced by the body are known as endocannabinoids, and lab-synthesized compounds are simply known as synthetic cannabinoids.

Primitive liverworts may contain substances related to THC (Apteryx australis). There is a plant known as the New Zealand liverwort, which produces an unusual type of cannabinoid (called perrottetinenic acid) that appears to be very closely related to THC, so much so that it may actually act on the CB1-receptor! If this is the case, it will be the only other known plant compound found in nature that is capable of doing so. However, whether or not this compound actually acts on the CB1-receptor is not yet known. But one thing we seem to know for sure: no other plant aside from cannabis produces THC.

Most cannabis enthusiasts will have heard of the classic cannabinoids such as THC, CBD, THCV and CBC, which for many years were thought to be the only compounds that acted on the cannabinoid receptors. The classic cannabinoids all share the same chemical formula, C21H30O2.

However, as our understanding of the endocannabinoid system has grown, we have found that the number and type of different compounds that act on the receptors is far larger.

Thus, we have to widen the goalposts somewhat as to what constitutes a cannabinoid—beyond the 120 or so classic cannabinoids, there are also an as-yet-undetermined number of related compounds, which also act on the receptors but do not share the classic structure.

And what on earth are cannabimimetics?

Helichrysum contains CBG or related compounds.

As well as cannabinoids, we also have an important class of non-classical cannabinoids known as cannabimimetics. They are called cannabimimetics as they literally mimic the biological activity of the classical cannabinoids, despite not sharing their structure.

Cannabimimetics are of increasing importance within the world of medicinal cannabinoid research. Classically, the EC system has been viewed as a simple set of two receptors and two ligands (a ligand is the term for a compound that binds to a receptor).

However, it is now increasingly being shown that the EC system is far more complex than this. Dozens of different compounds are now known to act either directly or indirectly on the EC system, and many of these compounds also work on other important biological messaging systems such as the opioid, serotonergic and dopaminergic signalling systems.

Some examples of known cannabimimetics:

NAE’s & N-alkylamides

N-acylethanolamines are a class of fatty acid compounds which are known to be heavily involved in biological signaling. NAE’s include N-arachidonoylethanolamine (better known as anandamide), N-palmitoylethanolamine (PEA), N-linoleoylethanolamide (LEA), and N-oleoylethanolamine (OEA).

NAE’s including OAE, PEA and LEA have been found to occur in many plant species. Notably, OAE and LEA have both been found in the cocoa plant, and black truffles have even been reported to contain anandamide itself! Lastly, the compounds known as N-alkylamides have been found in various echinacea species, and it is thought that echinacea’s importance in herbal medicine may derive from this fact.

Echinacea has been found to contain cannabimimetic N-alkyamides.

Anandamide is well known for being the biological compound which most closely resembles the activity of THC, as it directly agonizes the principal cannabinoid receptors. It is now also known that anandamide also directly agonizes a third cannabinoid receptor known as GPR119, which is also affected by N-oleoylethanolamine.

As well as directly acting on the principal and minor cannabinoid receptors, NAE’s are also known to exert a range of indirect effects. For example, LEA, PEA and OEA all inhibit levels of the FAAH enzyme that is responsible for degrading anandamide itself, and thus can effectively increase levels of anandamide in tissues over time.

N-alkylamides are a similar but less well-researched class of cannabimimetic compounds that have been shown to exert selective effects on the CB2-receptors, and have been shown to exert anti-inflammatory effects similar to anandamide.

Beta-caryophyllene

This important terpene is found in cannabis, and its oxide (which forms on contact with air) is the compound detected by drug-sniffing dogs! B-caryophyllene has been shown to act as a full agonist of the CB2-receptor (in the body), although it does not act on the CB1-receptor (in the brain).

It has also been shown to exert anti-inflammatory and analgesic effects in mice, but not in mice bred to lack CB2-receptors—showing that this biological activity is exerted via the receptors themselves.

Salvinorin A

Salvinorin A is the main component of the psychoactive plant species Salvia divinorum. Unusually for a hallucinogenic plant compound, salvinorin A is a terpenoid, not an alkaloid like mescaline, psilocybin and DMT. Furthermore, it is a dissociative, rather than a classic hallucinogen.

Interestingly, it seems that salvinorin A does not interact with the classic cannabinoid receptors, but in fact interacts with a putative third cannabinoid receptor that apparently forms only in inflammatory conditions, and which also acts as a kappa-opioid receptor. The κ-opioid receptors are fundamental to pain regulation, and are also the principal target of most hallucinatory compounds!

Salvinorin A is much rarer, and appears to only be found in high quantities in S. divinorum itself. However, there are indications that other sage species may also contain traces of the compound itself, or closely related molecules.

Myrcene

The Chinese rhododendron has been shown to contain CBC or related compounds.

Another very important terpene found in cannabis, and one that is also a major constituent of the essential oil of hops (Humulus lupulis). Although it is not thought that myrcene directly acts on the cannabinoid receptors, it is now known that its biological activity alters the psychoactive effect of THC.

Myrcene is known to be present in high levels in strains that exert a ‘stoney’ or ‘couchlock’ effect on the user. The sedative effects of myrcene-containing plants such as hops and verbena have been known for millennia, and it is now thought that the sedative effect is due to myrcene’s ability to agonise (activate) the opioid receptors (studies have shown that the opioid antagonist naxalone blocks myrcene’s effects, suggesting that myrcene is an agonist).

Thus, although myrcene isn’t typically classed as a cannabinoid in the currently existing scientific literature, it certainly affects the subjective experience of the cannabis ‘high’. Further research will no doubt determine the exact nature of the link; presently, while testing labs such as Steep Hill Halent in California have been collecting data on the association for years, no formal studies have as yet been conducted.

Plants that produce ‘cannabimimetic’ compounds

First off, there are abundant plant sources of terpenes such as β-caryophyllene and myrcene, although of course, some sources are better than others. Myrcene is found in extremely high concentrations in hop oil, making up almost 80% of the extracted volume in some varieties, and is also found in high levels in mangoes, lemongrass, thyme, and verbena.

B-caryophyllene is found in black pepper, cloves, rosemary, hops, caraway, oregano, basil, lavender, cinnamon, and many more plant species. In most of these species, β-caryophyllene is a major constituent of the essential oil (comprising 20% in some hop species).

CBD-like compounds were recently discovered in flax seeds.

In time, the list of plants that can safely be said to contain cannabimimetic compounds will no doubt expand dramatically, as we continue to find compounds capable of acting on the EC system.

But do any plants produce classical cannabinoids, other than cannabis?

Up until very recently indeed, it seemed that the cannabis plant was unique in producing the true, classic cannabinoids. However, this conventional wisdom appears to have been turned on its head with the discovery in 2012 that flax (linseed) seeds produce cannabidiol (CBD)! Or at least, that they produce cannabinoid-like compounds very similar to CBD, which appear to have similar anti-inflammatory effects.

However, there is in fact a much earlier piece of research suggesting that the compound cannabigerol (CBG) and its precursor cannabigerolic acid (CBGA) are present in a South African herb, and a more recent (2011) study suggesting that cannabichromene (CBC) and some related compounds are present in Chinese rhododendron.

Edited and adapted and updated 2017. With thanks to Seshata 2015 online.

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For interest and as comparative information the following data is given regarding the Chinese herbal medicine Huo Ma Ren

Chinese name: Huo Ma Ren
Cannabis Seed Tincture (zero CBDs)

Herbactive has Cannabis Seed Tincture made from Chinese denatured cannabis seeds. This has zero THC or CBD. NB Do not confuse this extract with the CBD Oil Herbactive supplies, see above.

The action of Cannabis seed tincture is as follows:

  • Cannabis sativa (Hemp, Cannabis seed, Huo Ma Ren, Chinese herbal medicine) -
  • Taste: Sweet, neutral.
  • Meridian: SP ST LI.
  • Action: Aperient/emollient.
  • Use: Constipation of the debilitated or aged person. Gentle laxative, increases peristalsis; lowers BP.
     

Nutritional Information – Organic Hemp (cannabis) Seed Oil

 

Typical nutritional values

per 100g

per Tablespoon (10g serving)

Energy

3700 kJ/900 kcal

 

Protein

0.0 g

0.0 g

Carbohydrate

0.0 g

0.0 g

-of which Sugar

0.0 g

0.0 g

Fat

100.0 g

10.0 g

-of which Saturates

9.2 g

0.9 g

-of which Monounsaturates

12.8 g

1.3 g

---of which Omega 9

12.3 g

1.2 g

-of which Polyunsaturates

78.0 g

7.8 g

---of which Omega 3

18.7 g

1.9 g

---of which Omega 6

56.6 g

5.7 g

-----of which Gamma-Linolenic Acid (GLA)

3.3 g

330 mg

--of which Cholesterol

0.0 g

0.0 g

Fibre

0.0 g

0.0 g

Sodium

0.0 g

0.0 g

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Prices of all our herbal products

Find out about herbal medicine for preventative treatment against developing cancer

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LiverDetox
WormLess Anti-parasitic Method
Adaptogenic (herbal blood cleanser)
You can buy specific tinctures for your health needs (to enhance your immune system and help improve the protection and prevention of cancer taking hold in the body): Astragalus, Cancer Bush (Sutherlandia), Mistletoe (Viscum), Curcuma (Turmeric), Baikal, Wireweed, Barbata, Echinacea, Vinca, Sweet Violet, etc. see and order from our products and prices page

 

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Cannabis sativa Tincture (Hemp, Cannabis seed, Huo Ma Ren)
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I supply legal hemp compound oil of cannabidiol (CBD) health-supplement at different entourage strengths (3%, 5%, 20%)

Used as a preventative/protective primarily suggested for:
serious illnesses
nausea from chemo and other drug treatments
spasms and pain
seizures
anxiety
muscle tension and pain
bacterial infections
nervous system damage and pain
diabetes
blood and circulation problems
psoriasis
Crohn's disease and diverticulitis
inflammatory conditions
bone pain
rheumatoid arthritis
antioxidant threat
hearing loss
vision loss
 

 

 


Prescriptions

Our herbal tonic medicines are carefully prepared on a personal and individual basis for your healing by medical herbalist Alan Hopking MA MNIMH FINEH.

Only whole herbs are used in our herbal medicines. Nothing else is added. If you have symptoms which you consider might be helped with herbal medicine please contact herbal practitioner Alan Hopking for a friendly confidential professional consultation. See terms and fees.

Once you have received your herbal prescription you can contact Alan Hopking at any time for more free advice (preferably by email). When you have completed your bottle of herbal medicine and if you want a repeat prescription you are requested to phone or email so that your progress can be assessed and adjustments made if necessary so that there is no break in your treatment. To order or re-order, click here.

MRCHM - see Alan Hopking's statement about renouncing his association with membership of this organisation

HERBACTIVE Centre of Herbal Medicine, England, UK. Freephone 0800 0834436

General advice to consumers on the use of herbal remedies from the Medicines Healthcare products Regulatory Agency

From the website of the Medicines Healthcare products Regulatory Agency (www.mhra.gov.uk) Department of Health, UK

• Remember that herbal remedies are medicines. As with any other medicine they are likely to have an effect on the body and should be used with care. • Herbal remedies may sometimes interact with other medicines. This makes it particularly important to tell your doctor or pharmacist if you are taking a herbal remedy with other medicines such as prescribed medicines (those provided through your doctor or dentist). • Treat with caution any suggestion that a herbal remedy is '100% safe' or is 'safe because it is natural'. Many plants, trees, fungi and algae can be poisonous to humans. It is worth remembering that many pharmaceuticals have been developed or derived from these sources because of the powerful compounds they contain. Any medicine, including herbal remedies, which have an effect on the body should be used with care. • Treat with caution any herbalist or other person who supplies herbal remedies if they are unwilling or unable to provide written information, in English, listing the ingredients of the herbal remedy they are providing. • If you are due to have a surgical operation you should always remember to tell your doctor about any herbal remedy that you are taking. • Anyone who has previously experienced any liver complaint, or any other serious health complaint is advised not to take any herbal remedy without speaking to their doctor first.

PRECAUTIONS:

Pregnant/Breast-feeding mothers

Few conventional medicines have been established as safe to take during pregnancy and it is generally recognised that no medicine should be taken unless the benefit to the mother outweighs any possible risk to the foetus. This rule should also be applied to herbal medicinal products. However, herbal products are often promoted to the public as being “natural” and completely “safe” alternatives to conventional medicines. Some herbal ingredients that specifically should be avoided or used with caution during pregnancy. As with conventional medicines, no herbal products should be taken during pregnancy unless the benefit outweighs the potential risk.

Volatile Oils

Many herbs are traditionally reputed to be abortifacient and for some this reputation can be attributed to their volatile oil component.(6) A number of volatile oils are irritant to the genito-urinary tract if ingested and may induce uterine contractions. Herbs that contain irritant volatile oils include ground ivy, juniper, parsley, pennyroyal, sage, tansy and yarrow. Some of these oils contain the terpenoid constituent, thujone, which is known to be abortifacient. Pennyroyal oil also contains the hepatotoxic terpenoid constituent, pulegone. A case of liver failure in a woman who ingested pennyroyal oil as an abortifacient has been documented.

Uteroactivity

A stimulant or spasmolytic action on uterine muscle has been documented for some herbal ingredients including blue cohosh, burdock, fenugreek, golden seal, hawthorn, jamaica dogwood, motherwort, nettle, raspberry, and vervain. Herbal Teas Increased awareness of the harmful effects associated with excessive tea and coffee consumption has prompted many individuals to switch to herbal teas. Whilst some herbal teas may offer pleasant alternatives to tea and coffee, some contain pharmacologically active herbal ingredients, which may have unpredictable effects depending on the quantity of tea consumed and strength of the brew. Some herbal teas contain laxative herbal ingredients such as senna, frangula, and cascara. In general stimulant laxative preparations are not recommended during pregnancy and the use of unstandardised laxative preparations is particularly unsuitable. A case of hepatotoxicity in a newborn baby has been documented in which the mother consumed a herbal tea during pregnancy as an expectorant. Following analysis the herbal tea was reported to contain pyrrolizidine alkaloids which are known to be hepatotoxic.

Breast-feeding mothers

A drug substance taken by a breast-feeding mother presents a hazard if it is transferred to the breast milk in pharmacologically or toxicologically significant amounts. Limited information is available regarding the safety of conventional medicines taken during breast-feeding. Much less information exists for herbal ingredients, and generally the use of herbal remedies is not recommended during lactation.

Paediatric Use

Herbal remedies have traditionally been used to treat both adults and children. Herbal remedies may offer a milder alternative to some conventional medicines, although the suitability of a herbal remedy needs to be considered with respect to quality, safety and efficacy. Herbal remedies should be used with caution in children and medical advice should be sought if in doubt. Chamomile is a popular remedy used to treat teething pains in babies. However, chamomile is known to contain allergenic sesquiterpene lactones and should therefore be used with caution. The administration of herbal teas to children needs to be considered carefully and professional advice may be needed.

Perioperative use

The need for patients to discontinue herbal medicinal products prior to surgery has recently been proposed. The authors considered eight commonly used herbal medicinal products (echinacea, ephedra, garlic, ginkgo, ginseng, kava, St John’s Wort, valerian). On the evidence available they concluded that the potential existed for direct pharmacological effects, pharmacodynamic interactions and pharmacokinetic interactions. The need for physicians to have a clear understanding of the herbal medicinal products being used by patients and to take a detailed history was highlighted. The American Society of Anaesthesiologists (ASA) has advised patients to tell their doctor if they are taking herbal products before surgery and has reported that a number of anaesthesiologists have reported significant changes in heart rate or blood pressure in some patients who have been taking herbal medicinal products including St John’s Wort, ginkgo and ginseng. MCA is currently investigating a serious adverse reaction associated with the use of ginkgo prior to surgery. In this case, the patient who was undergoing hip replacement experienced uncontrolled bleeding thought to be related to the use of ginkgo.

From the website of the Medicines Healthcare products Regulatory Agency (www.mhra.gov.uk) Department of Health, UK

Donation

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